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N,N'-Carbonyldiimidazole (CDI)
N,N'-Carbonyldiimidazole is an organic compound with the molecular formula (C3H3N2)2CO, also known as CDI or 1,1' – carbonyldiimidazole, CAS No.530-62-1. It is a white or slightly yellowish crystalline powder with high reactivity. CDI is often used as an efficient coupling agent in organic synthesis, particularly in peptide synthesis and protein chemistry. It can react with amino acids, peptides, amines, and other compounds containing active hydrogen to form corresponding amide bonds.
- Overview
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Molecular-structure：
Applications:
N,N’-Carbonyldiimidazole (CDI) can be used for peptide synthesis which is an effective coupling agent in the formation of peptide bonds, facilitating the synthesis of peptides in pharmaceutical manufacturing. It is also the good reagent for selective modification of amino acids in proteins. In organic synthesis, CDI is a versatile reagent, especially in the preparation of imidazole derivatives, which are valuable in medicinal chemistry.
Specifications:
Product |
QC Inspection Items |
Specifications |
|
N,N’-Carbonyldiimidazole (CDI) |
Appearance |
white crystalline powder |
Assay (GC, area%) |
≥98% (a/a) |
|
Melting range (lower value) |
≥115℃ |
|
Melting range (upper value) |
≤122℃ |
Competitive Advantage:
We use Triphosgene (BTC) to replace phosgene for CDI production, which is a safer chemical process. In addition, the by-product imidazole hydrochloride is fully recovered for conversion to imidazole for recycling in CDI synthesis. We take the advantage from this technology to have less wastes and lower production cost for competitiveness.
Tag:
N,N'-Carbonyldiimidazole, CAS No.530-62-1, efficient coupling agent, peptide bonds
